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EGTTI began operations in 1967 as a technical secondary school. The management admitted its first batch of students at Sigalagala Technical and Trade School while they awaited completion of Kisumu Technical Secondary School which Former Education Minister the late Dr. Taaitta Toweett officially opened in 1971.


In 1988, the Ministry upgraded the institution to a Technical Training Institute, the aim being to produce hands-on human resource, competent in the application of technical skills. This coincided with the national roll-out of the 8-4-4 education curriculum that required such institutions to cater for the rising demand for technical skills.


In 1996, the Ministry further upgraded the Technical Training Institute into a National Polytechnic to cater for the regional demand for technical skills. Retired President, Daniel Toroitich Arap Moi inaugurated the new status on June 21, 1997.


On 22nd August, 2014 in response to section 26 (2) of the Technical and Vocational Education and Training Act of 2013, the Cabinet Secretary for Education Science and Technology promulgated the  NYAMIRA NATIONAL POLYTECHNIC ORDER, 2014 with a wider mandate that has now occasioned the new name.


This new order required the institution to constitute a Governing Council to steer it and repeal Legal Notice No 85 of May 30, 2001 that recognized it as a polytechnic. The Governing Council assumed office on August 2015.